Are you looking for ketamine treatment in New York City? Ketamine has been used as an anesthetic around the world since its FDA approval in 1970. It has been used extensively for pediatric and adult treatment in surgical applications, emergency departments, ambulances, trauma medicine, and combat zones. It is also commonly used in veterinary medicine. It is so widely used that the World Health Organization even lists it as one of the most essential medicines due to its therapeutic effects and the wide margin of safety.
Research in the last two decades done by institutions like Yale and the National Institutes of Health has identified ketamine as an important breakthrough in the treatment of mood disorders and chronic pain.
Ketamine has been shown to reduce symptoms of mood disorders and chronic pain conditions alike. Unlike some other antidepressants that can take 3-6 weeks for the therapeutic effects to take place, ketamine is very rapid and for some can improve their depression within hours. Ketamine’s primary effect pathway is as a partial antagonist of the NMDA receptor and works on the glutamate system within the brain. It also increases BDNF within the brain, a protein that increases connections between neurons and is the cause of change or neuroplasticity within the brain. The antidepressant effects of ketamine-induced BDNF release were confirmed by a recent study. Ketamine is also active at a number of other neuroreceptor sites within the brain.
The amygdala is the part of the brain that handles fear and emotion. Ketamine can increase activity in the prefrontal cortex of the brain, the part of the brain responsible for executive control. By strengthening the connection between the prefrontal cortex and the amygdala, ketamine allows greater control over our emotional reactivity. This can be very helpful for mood disorders and for those who have a history of PTSD or childhood trauma. Ketamine sessions can allow ingrained habits of thought, feeling, perception, and understanding to recede, diffuse and break down. It can disrupt rigid or maladaptive mental structures, loosen defense mechanisms and change self-narratives. In doing so, patients can develop new understandings and reclaim disconnected parts of themselves. Ketamine can foster greater access to the subconscious mind while also allowing greater self-acceptance, self-transcendence, and an expanded sense of meaning in their lives.
Originally used as a surgical anesthetic, ketamine has emerged in recent years as a highly effective depression drug for many, particularly those who have not responded well to traditional antidepressants and other treatments.
Ketamine provides a short-term remission of symptoms in many patients, with about 85 percent of our patients experiencing substantial improvement of symptoms after ketamine treatment, with many patients experiencing relief within hours of first treatment.
Ketamine’s fast-acting results likely have to do with the fact that it affects a different part of the brain than normal antidepressant medications. Studies have shown that ketamine temporarily blocks the brain receptors are known as NMDA receptors, which are damaged by mental illnesses like depression. This temporary blockage functions similarly to hitting a reset or refresh button, which, in turn, triggers these receptors to resume normal function.